The Nuremberg Code originated as a response to which of the following?

• A. It was created in response to Nazi experiments.
• B. It established the Common Rule.
• C. It regulated placebo use in trials.
• D. It addressed animal ethics.

Answer: (A)

The main idea is that the Nuremberg Code originated as a direct reaction to the Nazi medical experiments conducted during World War II and exposed in the Nuremberg Doctors’ Trial. The horrific abuses compelled the creation of a formal set of ethical guidelines for human experimentation, centering on voluntary informed consent, minimizing harm, and ensuring that research is scientifically valid and necessary. The other statements don’t fit this origin: the Common Rule is a later U.S. framework for protecting human subjects; regulating placebo use was not what sparked the Code; and animal ethics is outside the scope of a code designed specifically for human experimentation.